Huntington’s disease – Symptoms, causes, and management

Huntington’s disease – Symptoms, causes, and management

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In the realm of neurological disorders, Huntington’s Disease (HD) stands as a formidable adversary, relentlessly encroaching upon the lives of those afflicted. HD is a hereditary, progressive neurodegenerative disorder that impairs both motor and cognitive functions, leading to a profound deterioration in an individual’s quality of life. With a genetic underpinning involving the expansion of CAG trinucleotide repeats, HD presents a complex clinical picture characterized by a range of motor symptoms, cognitive impairments, and psychiatric manifestations. Motor symptoms Chorea One of the hallmark symptoms of Huntington’s Disease is chorea, characterized by involuntary, jerky, and unpredictable movements of the limbs, face, and other body parts. These movements can be mild or severe and often interfere with activities of daily living. Dystonia Individuals with HD may experience muscle contractions and abnormal postures known as dystonia. This symptom can lead to sustained muscle contractions, causing discomfort and difficulty maintaining a normal posture. Bradykinesia As the disease progresses, individuals may develop bradykinesia, a slowness of voluntary movements. This can affect one’s ability to initiate and complete tasks. Impaired coordination Huntington’s disease often leads to impaired coordination and balance. Individuals may have difficulty walking and may become prone to falls. Difficulty swallowing Dysphagia, or difficulty swallowing, is a common symptom in advanced stages of HD.
12 silent shared symptoms of Parkinson’s and TD

12 silent shared symptoms of Parkinson’s and TD

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Parkinson’s Disease (PD) and Tardive Dyskinesia (TD) are very different neurological conditions that often share distinctive symptoms. While PD is a progressive neurodegenerative condition primarily characterized by motor impairments, TD can cause problems with motor skills, often affecting arms, legs, face, and neck. However, both conditions may manifest silent symptoms that can easily be missed. Hence, this article explains the conditions and focuses on the overlapping silent symptoms of PD and TD. But before delving into the shared silent symptoms, one must understand the basics of PD and TD. Understanding Parkinson’s Disease and Tardive Dyskinesia Parkinson’s Parkinson’s is a complex neurodegenerative disorder resulting from losing dopamine-producing cells in the brain. Its hallmark motor symptoms include tremors, bradykinesia (slowness of movement), rigidity, and postural instability. However, the non-motor symptoms often go unnoticed or are mistaken for other health issues. Tardive Dyskinesia (TD) TD is a movement disorder that can affect certain body parts and contribute to involuntary, repetitive movements, primarily affecting the face, lips, tongue, and sometimes limbs. While there is not much information on how the symptoms begin, one can consider chronic blockage of dopamine as one of the leading causes. Now that one has basic information on these disorders, let’s focus on the shared symptoms of PD and TD that one may miss.

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